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Home: Welcome

UNDERSTANDING MECHANISMS OF RISK AND RESILIENCE THROUGHOUT BRAIN & BEHAVIOR DEVELOPMENT

Home: Our Story

CHALLENGES THAT DRIVE US

  • To understand why some youths who grow up with developmental stress become suicidal, while others do not (resilient).

  • To timely identify those at risk for serious psychopathology and divert the developmental trajectory from risk to resilience.

QUESTIONS WE ASK

  • What are the mechanisms that drive variability in the development of brain and behavior? 

  • How do environmental (E) exposures (e.g., trauma, neighborhood environment) interact among themselves (E X E), and with biological (e.g., genetic (G)) factors (G X E), to shape developmental trajectories of youth?

OUR VISION

  • Promote resilience and prevent suicide and serious psychiatric outcomes in youths.

OUR MISSION

  • Conduct impactful translational science aimed at reducing youth mental health burden.

Home: About

OUR RESEARCH

In the BarziLab, we use multiple methods to understand variability in the development of brain and behavior.

5 pillars of the research_v2.png

We study how a myriad of environmental exposures (such as trauma and socioeconomic factors) dynamically interact among themselves, and with biological factors (such as genetic and epigenetic) to shape the development of brain and behavior.

Home: Our Values

OUR VALUES

We collect and analyze large human datasets.

We do collaborative interdisciplinary science.

We work with basic scientists to inform mechanistic gaps that can only be investigated in animal models.

Home: Recent Publications

RECENT PUBLICATIONS

Smartphone ownership, age of smartphone acquisition, and health outcomes in early adolescence

2026

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Pediatrics

Prevalence of suicidal ideation and suicide attempts by race and gender in three large U.S. adolescent cohorts

2025

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American Journal of Psychiatry

Postnatal vs prenatal maternal stress and offspring neurodevelopment

2025

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JAMA Network Open

A calibrated sensitivity analysis for weighted causal decompositions

2025

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Statistics in Medicine

Adolescent depressive symptom trajectories from before to after the COVID-19 pandemic

2025

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JAMA Network Open

Prediction of adolescent suicide attempt by integrating clinical, neurocognitive and geocoded neighborhood environment data

2025

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Schizophrenia Bulletin

Mental health, minority stressors, and resilience factors among early adolescent immigrant youth

2025

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Journal of the American Academy of Child and Adolescent Psychiatry

Engaging voices, shaping futures: Lessons from a youth advisory board on Black youth suicide prevention

2025

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Journal of the American Academy of Child and Adolescent Psychiatry

Probing the digital exposome: Associations of social media use patterns with youth mental health

2024

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NPP—Digital Psychiatry and Neuroscience

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Lifespan Brain Institute (LiBI)

University of Pennsylvania

Children’s Hospital of Philadelphia

 

 

©2020 by BARZILAB. Designed by Moti Barzilay

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